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A Review of Mood and Brain Health Research



A study by the George Eby Research Institute, published in the Journal of Medical Hypothesis, reports, "Since inadequate brain magnesium appears to reduce serotonin levels, and since anti-depressants have been shown to have the action of raising brain magnesium, we further hypothesize that magnesium treatment will be found beneficial for nearly all depressives and treatment resistant depression."

Symptoms of possible magnesium deficiency syndrome (Hypomagnesemia) include:

Altered immune responses, alcoholism, arrhythmias, asthma, ataxia, attention deficit hyperactivity disorder (ADHD), chronic fatigue syndrome (CFS), circulatory disturbances (arteriosclerosis, cardiac infarction, stroke), premenstrual cramps (PMS), depression, diabetes mellitus, epilepsy, hypertension, migraine, neurodegenerative disorders, multiple sclerosis (MS), obesity, osteoporosis, Parkinson's, preeclampsia, stress dependent disorders,

IntraCellular Magnesium

Mg Citrate and Mg Oxide, among others, are incapable of intracellular absorption. See: Magnesium. What's the best kind?

Magnesium: An Essential Mineral for Optimal Health

Department of Family Medicine,

Research has shown that the mineral content of magnesium in food sources is declining, and that magnesium depletion has been detected in persons with some chronic diseases. This has led to an increased awareness of proper magnesium intake and its potential therapeutic role in a number of medical conditions. Studies have shown the effectiveness of magnesium in eclampsia and preeclampsia, arrhythmia, severe asthma, and migraine. Other areas that have shown promising results include lowering the risk of metabolic syndrome, improving glucose and insulin metabolism, relieving symptoms of dysmenorrhea, and alleviating leg cramps in women who are pregnant. The use of magnesium for constipation and dyspepsia are accepted as standard care despite limited evidence. Although it is safe in selected patients at appropriate dosages, magnesium may cause adverse effects or death at high dosages. Because magnesium is excreted renally, it should be used with caution in patients with kidney disease. Food sources of magnesium include green leafy vegetables, nuts, legumes, and whole grains.

Proper Breathing: Lowers CO2 - Increases Mg2

Anxiety and respiratory patterns: their relationship during mental stress and physical load.

Central respiratory chemosensitivity is an essential mechanism that, via regulation of breathing, maintains constant levels of blood and brain pH and partial pressure of CO2.

Increased brain-pCO2, acidic cytosol pH and/or increased basal cytosolic Ca2+ level diminish inward Ca2+-current into cytosol, decrease arousal--they may cause dysthymia or depression. This state usually co-exists with ATP-deficiency and decreased cytosolic Mg2+ content.

Coexisting Issues - Allergies and Mental Health

A magnesium-deficient brain is also more susceptible to allergens, foreign substances that can cause symptoms similar to mental illness disorder.

Wendy Wells

Author Wendy Wells NMD, accredited naturopath physician in Arizona. Call and schedule a 15 minute phone consultation, at no cost.

Tangle of Wires

Neurotransmitters and hormones for happiness? Treatments for concentration and memory improvement.

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Updated: Jan 8 2015