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Ginger Root Limits Cancer Cells By 50%

Authors Wendy Wells NMD, Jason Jensen, NMD.

In the 2014 August edition of "In Vitro Cellular & Developmental Biology," researchers present evidence demonstrating dose dependent affects of gingeraol-10, a compound shown to limit growth of human cancer cells by 50%.[1]

Ginger root, Zingiber officinale, is made up of hundreds biologically active compounds that include gingeraols and shogaols, which are of special interest to medical researchers for their toxic affects on human cancer cells. These compounds alter chemical pathways, shown to inhibit human cancer growth, involving a process called "apoptosis," a series of chemically programmed DNA events leading to the natural demise of cancer cells without affecting healthy surrounding tissue.

The chemo-therapy potential of these compounds have been studied for years by universities around the world. Another recent study from the Rajiv Gandhi Centre for Biotechnology in India, was published in Aug 2014, involving colon cancer cells. Using a mouse model study, they successfully mapped the molecular pathways of Ginerol-6, providing evidence for ginger root's anticancer and chemo-preventive properties. [2]

References:

1. [10]-Gingerol induces mitochondrial apoptosis through activation of MAPK pathway in HCT116 human colon cancer cells. 2014 Aug 23.

2. [6]-Gingerol Induces Caspase-Dependent Apoptosis and Prevents PMA-Induced Proliferation in Colon Cancer Cells by Inhibiting MAPK/AP-1 Signaling.

3. Ginger Compound [6]-Shogaol and Its Cysteine-Conjugated Metabolite (M2) Activate Nrf2 in Colon Epithelial Cells in Vitro and in Vivo.


Wendy Wells
Wendy Wells NMD, naturopath medical doctor.
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Jason Jensen
Jason Jensen NMD, naturopathic medical doctor.
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Updated: Jan 8 2015